Turn your Instant Pot on Saute mode and add the oil and onion. Saute until the onion is fragrant and translucent. Scoot the onion off to the side and add the beef stew meat. Brown meat for 2 to 3 minutes on two sides.
Add the remaining ingredients in the order in which they appear on the ingredient list. Give everything a big stir, secure the lid on the Instant Pot and cook on the Stew/Meat mode for 30 minutes. Keep the pressure release valve set to Sealing. Once the Instant Pot has run its course, allow it to go into Keep Warm mode for 20 minutes. Release any remaining pressure (if any).
If you'd like to thicken the stew, put the Instant Pot back on the Saute mode and add the tapioca flour. Stir well and allow stew to boil 5 to 8 minutes until it begins to thicken up.
Serve with your favorite homemade gluten-free bread and enjoy!
*Replace red wine with more beef broth or 1 cup Guinness